chelating agent

CALCIUM DISODIUM EDTA

sodium calcium edetate

chelating agent
CAS Number:62-33-9

INCI Name

CALCIUM DISODIUM EDT...

Functions

1 Roles

Sustainability

N/A

Category

chelating agent

What It Does

Calciate(2-), [[N,N'-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)-N,N',O,O',O(N)-,O(N')-]-, disodium

Molecular Profile

Molecular Weight

374.27

g/mol

H-Bond Donors

0

Hydrogen bond donor count

H-Bond Acceptors

10

Hydrogen bond acceptor count

Polar Surface Area

167.0

Angstroms squared

PubChem CID

6093170

View on PubChem

Ingredient Attributes

Ingredient Compatibility

Known Interactions

COPPER TRIPEPTIDE-1Use CautionChelation

EDTA is a strong chelator that can strip copper from peptide complexes, deactivating GHK-Cu. Avoid EDTA as a chelating agent in copper peptide formulations; use a non-competing alternative.

IRONUse CautionAbsorption Competition

Calcium inhibits both heme and non-heme iron absorption by 50-60% when taken together. These minerals compete for the same absorption pathways. Separate by at least 2 hours or formulate for different serving times.

ZINCNoteAbsorption Competition

High-dose Calcium (>600mg) can reduce Zinc absorption by 30-50%. Consider separating doses or using chelated zinc (zinc bisglycinate) for better absorption.

MAGNESIUMNoteAbsorption Competition

Calcium and Magnesium compete for absorption at high doses. While they can be combined at moderate levels, high-dose formulations should separate them or use chelated forms.

CITRIC ACIDNotePrecipitation

High Calcium + Citric Acid can form calcium citrate precipitate in beverages, causing cloudiness or sedimentation. Manageable with proper formulation (sequestrants, pH control), but test stability.

Compatibility analysis powered by OpenMix — open-source formulation science

Quick Reference

Full INCI Name
CALCIUM DISODIUM EDTA
Common Name
sodium calcium edetate
CAS Number
62-33-9
Category
chelating agent

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