general100% Pure Liquid

Dimethyl Isosorbide

Dimethyl Isosorbide

solventviscosity modifier
CAS Number:5306-85-4

INCI Name

Dimethyl Isosorbide

Functions

2 Roles

Sustainability

8/10

Category

general

What It Does

Dimethyl Isosorbide is a bio-based solvent derived from renewable plant sugars (typically corn glucose) that has become highly valued in modern cosmetic formulations for its exceptional ability to enhance the penetration and efficacy of active ingredients without irritation. Unlike traditional solvents, it offers a unique dual functionality: it dissolves both hydrophilic and lipophilic actives while simultaneously improving their delivery into skin, making it particularly popular in high-performance serums containing retinoids, peptides, and antioxidants. Formulators choose it for its elegant skin feel, lack of tackiness, and ability to boost active ingredient performance at concentrations of 1-10%.

Dissolves active ingredients
Enables proper formulation
Affects product penetration
Controls evaporation rate

Technical Properties

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

thinning

Impact on formula thickness

Foaming Ability

none

Lather generation

Ingredient Compatibility

Works Well With

most activesantioxidantspeptidesretinoidsniacinamidevitamin C derivativesbotanical extractsmost emollients

Avoid Combining

highly alkaline ingredientsstrong oxidizers
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

8/10

Biodegradability

readily biodegradable

Source

plant-derived

Feedstock

corn-derived glucose (isosorbide base)

Quick Reference

Full INCI Name
Dimethyl Isosorbide
Common Name
Dimethyl Isosorbide
CAS Number
5306-85-4
Category
general

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