activesLiquid Solution

Glycerin, Aqua, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7

Matrixyl 3000

conditioningantioxidantfilm former

INCI Name

Glycerin, Aqua, Buty...

Functions

3 Roles

Sustainability

6/10

Category

actives

What It Does

Matrixyl 3000 is a patented anti-aging peptide complex combining palmitoyl oligopeptide (Matrixyl) and palmitoyl tetrapeptide-7 (Matrixyl 3000) in a stabilized aqueous delivery system. This specific formulation was developed by Sederma to stimulate collagen synthesis and repair damaged collagen matrices, with clinical studies showing visible reduction in wrinkle depth and volume. Formulators choose this pre-made solution for its proven efficacy at 3-5% usage levels and its ability to deliver lipophilic peptides in water-based formulations through the polysorbate 20 solubilization system.

Improves slip and manageability
Reduces static and frizz
Adds shine and smoothness
Protects from mechanical damage

Technical Properties

pH Range

5.0-7.0

Optimal working range

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

thickening

Impact on formula thickness

Foaming Ability

low

Lather generation

Ingredient Compatibility

Works Well With

nonionic surfactantshumectantsmost emollientshyaluronic acidother peptidesantioxidantsniacinamide

Avoid Combining

strong acidsstrong oxidizershigh concentrations of AHAsdirect vitamin C (ascorbic acid)retinol at high pH
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

6/10

Biodegradability

readily biodegradable

Source

mixed

Feedstock

The peptides are synthetically produced through solid-phase peptide synthesis, while the delivery system uses plant-derived glycerin, synthetic butylene glycol, and petroleum-derived carbomer

Quick Reference

Full INCI Name
Glycerin, Aqua, Butylene Glycol, Carbomer, Polysorbate 20, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7
Common Name
Matrixyl 3000
Category
actives

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