activesStandard

Nicotinamide Adenine Dinucleotide

NAD+

antioxidantconditioningskin protectant
CAS Number:53-84-9

INCI Name

Nicotinamide Adenine...

Functions

3 Roles

Sustainability

7/10

Category

actives

What It Does

Nicotinamide Adenine Dinucleotide (NAD+) is a critical coenzyme found in all living cells that plays a fundamental role in cellular energy metabolism and DNA repair processes. In cosmetic formulations, NAD+ is valued for its ability to support cellular regeneration, enhance mitochondrial function in skin cells, and provide potent antioxidant protection against environmental stressors. Formulators choose NAD+ for its scientifically-backed anti-aging properties, though it requires careful formulation due to its sensitivity to pH and oxidative conditions, and is typically used in premium skincare products targeting cellular rejuvenation and age-related skin concerns.

Neutralizes damaging free radicals
Protects skin from environmental stress
Prevents formula oxidation
Supports anti-aging benefits

Technical Properties

pH Range

5.0-7.0

Optimal working range

Ionic Charge

anionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Ingredient Compatibility

Works Well With

nonionic surfactantshumectantspeptidesmost emollientsother antioxidants

Avoid Combining

strong oxidizershigh concentrations of reducing agentsextreme pH conditions (below 4 or above 8)
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

fermentation

Feedstock

yeast or bacterial fermentation using glucose substrates

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