actives0.5% Standardized Solution

Sodium DNA

PDRN Solution

conditioningskin protectanthumectant

INCI Name

Sodium DNA

Functions

3 Roles

Sustainability

7/10

Category

actives

What It Does

Sodium DNA, particularly in its PDRN (polydeoxyribonucleotide) form, consists of low molecular weight DNA fragments typically extracted from salmon milt or produced through bacterial fermentation. This ingredient is valued in cosmetics for its ability to promote cellular regeneration and wound healing through purinergic receptor activation, making it particularly popular in Korean skincare formulations. Formulators choose it for its documented ability to stimulate fibroblast proliferation and collagen synthesis, with the 0.5% concentration being clinically studied for optimal efficacy in skin repair applications.

Improves slip and manageability
Reduces static and frizz
Adds shine and smoothness
Protects from mechanical damage

Technical Properties

pH Range

6.0-8.0

Optimal working range

Ionic Charge

anionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Foaming Ability

none

Lather generation

Ingredient Compatibility

Works Well With

nonionic surfactantshumectantspeptideshyaluronic acidmost emollients

Avoid Combining

strong cationic polymersstrong acidsheavy metal ionsDNase enzymes
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

fermentation

Feedstock

salmon milt or bacterial fermentation

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