INCI Name
Sodium DNA
Functions
3 Roles
Sustainability
7/10
Category
actives
What It Does
Sodium DNA, particularly in its PDRN (polydeoxyribonucleotide) form, consists of low molecular weight DNA fragments typically extracted from salmon milt or produced through bacterial fermentation. This ingredient is valued in cosmetics for its ability to promote cellular regeneration and wound healing through purinergic receptor activation, making it particularly popular in Korean skincare formulations. Formulators choose it for its documented ability to stimulate fibroblast proliferation and collagen synthesis, with the 0.5% concentration being clinically studied for optimal efficacy in skin repair applications.
Technical Properties
pH Range
6.0-8.0
Optimal working range
Ionic Charge
anionic
Molecular charge type
Viscosity Effect
neutral
Impact on formula thickness
Foaming Ability
none
Lather generation
Ingredient Compatibility
Works Well With
Avoid Combining
Sustainability Profile
Sustainability Score
Biodegradability
readily biodegradable
Source
fermentation
Feedstock
salmon milt or bacterial fermentation
Related Ingredients
Similar conditionings to explore
Ceramide NP
Ceramide Complex
Lavender Flower Extract
Encapsulated Matrixyl 3000 Spheres
Peppermint Oil
Available Variants
3 forms available
0.5% Standardized Solution
Aqueous Solution (0.02% active PDRN in water, cosmetic grade, microalgae-derived)
Aqueous Solution standardized to PDRN content (typically 0.2-0.5% active polynucleotide in solution; 4% of solution delivers ~0.008-0.02% active PDRN), microalgae-sourced (Chlorella or Arthrospira), vegan-certified, MW 50-1500 kDa (Revinage PDRN Vegan, Contipro, or equivalent)
Quick Reference
- Full INCI Name
- Sodium DNA
- Common Name
- PDRN Solution
- Category
- actives