humectants75% Aqueous Solution

Panthenol

Panthenol

humectantconditioningskin protectant
CAS Number:81-13-0

INCI Name

Panthenol

Functions

3 Roles

Sustainability

7/10

Category

humectants

What It Does

Panthenol is the stable alcohol analog of pantothenic acid (vitamin B5) that readily converts to the vitamin once absorbed into skin or hair. It's exceptionally valued in cosmetics for its dual hygroscopic and penetrative properties—it can hold moisture while also penetrating the hair shaft and skin layers to provide deep conditioning. Formulators favor panthenol because it's highly stable across typical cosmetic pH ranges, compatible with virtually all ingredient classes, and delivers visible improvements in skin smoothness and hair manageability at concentrations as low as 1-5%.

Attracts moisture from the air
Provides deep, lasting hydration
Improves skin elasticity and plumpness
Enhances penetration of other actives

Technical Properties

pH Range

4.0-7.0

Optimal working range

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Foaming Ability

none

Lather generation

Molecular Profile

Molecular Weight

205.25

g/mol

LogP

-0.90

Partition coefficient (lipophilicity)

H-Bond Donors

4

Hydrogen bond donor count

H-Bond Acceptors

4

Hydrogen bond acceptor count

Polar Surface Area

89.8

Angstroms squared

PubChem CID

131204

View on PubChem

Ingredient Compatibility

Works Well With

most surfactantshumectantsemollientsproteinspreservativesbotanical extracts

Avoid Combining

strong oxidizersextreme pH conditions (below 3 or above 10)
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

synthetic

Feedstock

pantothenic acid (vitamin B5) derivative

Available Variants

45 forms available

75% Aqueous Solution

75% Liquid Solution

75% Solution

Crystalline Powder, USP Grade

D-Panthenol 75% Liquid (in water carrier; dose accounts for 75% activity)

D-Panthenol, 75% Liquid (DL-Panthenol liquid in water carrier)

DL-Panthenol 75% Liquid

DL-Panthenol 75% Liquid (cosmetic grade)

DL-Panthenol 75% Liquid or 100% Powder

DL-Panthenol 75% Solution

DL-Panthenol Fine Powder, 98%

DL-Panthenol Liquid

DL-Panthenol Liquid (75% Aqueous Solution)

DL-Panthenol Liquid 50%

DL-Panthenol Liquid 75%

DL-Panthenol Powder (98% min purity, Spray-Dried)

DL-Panthenol, 75% Liquid

DL-Panthenol, 75% Liquid (cosmetic grade)

DL-Panthenol, 75% Liquid (dose 1.33% of liquid for 1% active panthenol — adjusted: using 100% pure liquid grade at 1.0%)

DL-Panthenol, 75% Viscous Liquid

Spray-Dried Powder on Maltodextrin Carrier (50-75% Panthenol content)

Standard

Viscous Liquid, 75% D-Panthenol (DL-form acceptable)

Viscous Liquid, DL-Panthenol 75% Solution

75% Aqueous Solution (DL-Panthenol)

75% DL-Panthenol Liquid (clear viscous liquid)

75% DL-Panthenol Liquid (in water/propylene glycol-free carrier)

75% DL-Panthenol Liquid (remainder is water carrier)

75% Liquid (DL-Panthenol, Cosmetic Grade)

75% Viscous Liquid (DL-Panthenol)

Clear Viscous Liquid, DL-Panthenol 75% Solution

D-Panthenol 75% liquid (dose calculated on 75% active basis; use 1.33% of 75% liquid to deliver 1.0% panthenol)

DL-Panthenol 75% Liquid (cosmetic grade)

DL-Panthenol, 100% Pure Viscous Liquid, cosmetic grade (75% D-form minimum)

DL-Panthenol, 75% Liquid

DL-Panthenol, 75% Liquid (cosmetic grade)

DL-Panthenol, 75% Liquid (in water), Cosmetic Grade

DL-Panthenol, 75% Liquid (Viscous)

DL-Panthenol, 75% Liquid in Water

DL-Panthenol, 75% liquid in water (D,L form), Cosmetic Grade

DL-Panthenol, 75% liquid in water (dose 2% of the solution for ~1.5% active panthenol)

DL-Panthenol, 75% Liquid in Water (dose accounts for 75% active)

DL-Panthenol, 75% liquid or 100% powder (cosmetic/USP grade)

Viscous Liquid (75% D-Panthenol, cosmetic grade)

Viscous Liquid (D-Panthenol 75% solution)

Quick Reference

Full INCI Name
Panthenol
Common Name
Panthenol
CAS Number
81-13-0
Category
humectants

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