humectants1% Aqueous Solution

Polyglutamic Acid

Polyglutamic Acid

humectantfilm formerskin protectant
CAS Number:25513-46-6

INCI Name

Polyglutamic Acid

Functions

3 Roles

Sustainability

8/10

Category

humectants

What It Does

Polyglutamic Acid (γ-PGA) is a naturally occurring biopolymer produced through bacterial fermentation of Bacillus subtilis, traditionally found in Japanese natto (fermented soybeans). This water-soluble anionic polypeptide is renowned for its exceptional moisture-binding capacity—reportedly holding up to 5000 times its weight in water, surpassing hyaluronic acid—while forming a breathable protective film on skin. Formulators favor it for its ability to enhance skin hydration without tackiness, improve the delivery of other actives, and provide a smooth, silky after-feel in serums and moisturizers.

Attracts moisture from the air
Provides deep, lasting hydration
Improves skin elasticity and plumpness
Enhances penetration of other actives

Technical Properties

pH Range

4.0-7.0

Optimal working range

Ionic Charge

anionic

Molecular charge type

Viscosity Effect

thickening

Impact on formula thickness

Foaming Ability

low

Lather generation

Ingredient Compatibility

Works Well With

nonionic surfactantsmost humectantspeptideshyaluronic acidglycerinbotanical extracts

Avoid Combining

strong cationic polymers at low pHhigh concentrations of multivalent metal ions
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

8/10

Biodegradability

readily biodegradable

Source

fermentation

Feedstock

bacterial fermentation of Bacillus subtilis

Available Variants

5 forms available

1% Aqueous Solution

1% Solution

High Molecular Weight Solution, 2% Aqueous

High MW Powder

Sodium Salt Solution 1%

Quick Reference

Full INCI Name
Polyglutamic Acid
Common Name
Polyglutamic Acid
CAS Number
25513-46-6
Category
humectants

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