chelating agents

Disodium EDTA

Disodium EDTA

chelating agentpreservative
CAS Number:139-33-3---6381-92-6

INCI Name

Disodium EDTA

Functions

2 Roles

Sustainability

4/10

Category

chelating agents

What It Does

Disodium EDTA is a synthetic chelating agent that binds metal ions like iron, copper, and calcium that can catalyze oxidation and destabilize formulations. It's the disodium salt of ethylenediaminetetraacetic acid, making it more water-soluble than the free acid form. Formulators choose it because it enhances the effectiveness of preservatives and antioxidants by sequestering trace metals that would otherwise promote rancidity and microbial growth.

Enhances formula performance
Contributes to product quality
Supports formulation goals
Improves user experience

Technical Properties

pH Range

4.0-6.0

Optimal working range

Ionic Charge

anionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Foaming Ability

none

Lather generation

Ingredient Compatibility

Known Interactions

COPPER PEPTIDEIncompatibleChelation

EDTA binds copper more strongly than the tripeptide does, so it strips copper from the complex and deactivates GHK-Cu. The damage is worst when EDTA approaches or exceeds the peptide in molar terms, which happens at LOW peptide doses. Remove the EDTA or replace it with a non-competing approach (trace-metal-controlled water, opaque airless packaging, and an antioxidant that does not reduce Cu2+).

IRONNoteChelation

EDTA chelates free iron strongly. Intentional in some applications (prevents oxidation catalysis) but can reduce iron bioavailability in supplements/beverages. Verify this is the intended behavior.

Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

4/10

Biodegradability

not readily biodegradable

Source

synthetic

Feedstock

petroleum-derived precursors

Quick Reference

Full INCI Name
Disodium EDTA
Common Name
Disodium EDTA
CAS Number
139-33-3---6381-92-6
Category
chelating agents

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