activesMicronized Powder USP Grade

Salicylic Acid

Salicylic Acid

exfoliantpreservativeantimicrobialph adjuster
CAS Number:69-72-7

INCI Name

Salicylic Acid

Functions

4 Roles

Sustainability

7/10

Category

actives

What It Does

Salicylic Acid is a lipophilic beta hydroxy acid derived synthetically from phenol, though historically extracted from willow bark. Unlike water-soluble AHAs, its oil-soluble nature allows it to penetrate into pores, making it uniquely effective for treating acne, blackheads, and oily skin conditions. Formulators choose it not only for its keratolytic exfoliation properties but also for its anti-inflammatory benefits and ability to function as a preservative at concentrations of 0.5% and above, though cosmetic exfoliation typically requires 0.5-2% in leave-on products.

Enhances formula performance
Contributes to product quality
Supports formulation goals
Improves user experience

Technical Properties

pH Range

3.0-4.0

Optimal working range

Ionic Charge

anionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Ingredient Compatibility

Known Interactions

RETINOLUse CautionpH Conflict

Retinol and Salicylic Acid together increase irritation risk. Salicylic Acid's optimal pH (2.5-4) destabilizes Retinol. Best used in separate routines.

GLYCOLIC ACIDUse CautionIrritation Risk

Combining AHA (Glycolic) and BHA (Salicylic) at full concentrations significantly increases irritation risk and can compromise the skin barrier. If combining, reduce concentrations of both.

LACTIC ACIDUse CautionIrritation Risk

Combining AHA (Lactic) and BHA (Salicylic) increases exfoliation beyond what most skin can tolerate. Reduce concentrations if combining, or use in separate products.

TRETINOINUse CautionIrritation Risk

Tretinoin combined with Salicylic Acid causes excessive exfoliation and irritation. Both are potent actives that thin the stratum corneum. Do not combine at full strength.

Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

synthetic

Feedstock

phenol derivative (originally from willow bark)

Available Variants

3 forms available

Micronized Powder USP Grade

Standard

USP Grade Micronized Powder

Quick Reference

Full INCI Name
Salicylic Acid
Common Name
Salicylic Acid
CAS Number
69-72-7
Category
actives

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