denaturant

ACETONE

acetone

denaturantsolvent
CAS Number:67-64-1

INCI Name

ACETONE

Functions

2 Roles

Sustainability

N/A

Category

denaturant

What It Does

Acetone

Molecular Profile

Molecular Weight

58.08

g/mol

LogP

-0.10

Partition coefficient (lipophilicity)

H-Bond Donors

0

Hydrogen bond donor count

H-Bond Acceptors

1

Hydrogen bond acceptor count

Polar Surface Area

17.1

Angstroms squared

PubChem CID

180

View on PubChem

Ingredient Attributes

Ingredient Compatibility

Known Interactions

AMINO ACID SOURCESIncompatiblemaillard_degradation

DHA undergoes Maillard browning with free amino acids on skin to produce melanoidins (the tan). Free amino acids IN THE FORMULA (aloe vera juice, hydrolyzed proteins, peptide complexes, amino acid blends) react with DHA pre-application, degrading the active and accelerating off-smell development over shelf life. Remove the amino-acid source, switch to glycerin/propanediol/sodium PCA for hydration, or use encapsulated DHA if the amino-acid ingredient is brand-critical.

ETHOXYLATED SURFACTANTUse Cautionperoxide_oxidation

Ethoxylated surfactants (Ceteareth-*, PEG-*, Polysorbate-*, Poloxamer-*) accumulate peroxides over shelf life via air oxidation of the polyoxyethylene chain. The resulting peroxides degrade DHA, accelerating off-smell and producing orange tones. For DHA formulations, prefer non-ethoxylated emulsifiers: Polyglyceryl-* esters (Polyglyceryl-6 Distearate, Polyglyceryl-10 Stearate), Lecithin, Sucrose Stearate, Olivem 1000 (Cetearyl Olivate + Sorbitan Olivate).

Compatibility analysis powered by OpenMix — open-source formulation science

Quick Reference

Full INCI Name
ACETONE
Common Name
acetone
CAS Number
67-64-1
Category
denaturant

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