Cholecalciferol (Vitamin D3) - Supports hormone synthesis, immune modulation, and skin cell differentiation; addresses common deficiency in women with hormonal concerns

INCI Name

Cholecalciferol

Functions

1 Roles

Sustainability

8/10

What It Does

Cholecalciferol is a fat-soluble secosteroid that functions as the most bioavailable form of vitamin D in topical applications. Unlike the traditional lanolin-derived D3, lichen-sourced cholecalciferol offers a vegan alternative while maintaining identical molecular structure and activity, making it particularly valued in clean beauty formulations. Its lipophilic nature requires oil-phase incorporation and protection from oxidation, but it demonstrates excellent stability when properly formulated with antioxidants in anhydrous or emulsion systems.

Enhances formula performance

Contributes to product quality

Supports formulation goals

Improves user experience

Technical Properties

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Ingredient Compatibility

Known Interactions

VITAMIN K2NoteAbsorption Competition

Vitamin D3 and K2 are often co-formulated beneficially (D3 increases calcium absorption, K2 directs it to bones). This is NOT an incompatibility — they are synergistic. Flag is informational: ensure K2 is included when high-dose D3 is used, to prevent soft tissue calcification.

Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

8/10

Biodegradability

readily biodegradable

Source

plant-derived

Feedstock

lichen extract (vegan alternative to lanolin-derived D3)

Quick Reference

Full INCI Name: Cholecalciferol
Common Name: Vitamin D3
Category: actives

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