INCI Name
Alpha-Arbutin
Functions
2 Roles
Sustainability
7/10
Category
actives
What It Does
Alpha-Arbutin is a biosynthetic glycosylated hydroquinone produced through enzymatic conversion, representing the alpha-anomer form which is significantly more stable and effective than its beta counterpart. This water-soluble active ingredient is specifically valued by formulators for its superior ability to inhibit tyrosinase activity without the cytotoxicity concerns associated with hydroquinone, making it a preferred choice for brightening and evening skin tone in concentrations typically ranging from 0.5-2%. Its enhanced stability at various pH levels and compatibility with other actives, combined with its non-irritating profile, has established it as a gold-standard ingredient in modern skin brightening formulations.
Technical Properties
pH Range
3.5-6.5
Optimal working range
Ionic Charge
nonionic
Molecular charge type
Viscosity Effect
neutral
Impact on formula thickness
Foaming Ability
none
Lather generation
Molecular Profile
Molecular Weight
272.25
g/mol
LogP
-0.70
Partition coefficient (lipophilicity)
H-Bond Donors
5
Hydrogen bond donor count
H-Bond Acceptors
7
Hydrogen bond acceptor count
Polar Surface Area
120.0
Angstroms squared
Ingredient Compatibility
Known Interactions
Arbutin is most stable and effective at pH 5-7, while L-Ascorbic Acid requires pH 2.5-3.5. Combined use forces a pH compromise that reduces efficacy of one or both. Use an Ascorbic Acid derivative if combining.
Sustainability Profile
Sustainability Score
Biodegradability
readily biodegradable
Source
synthetic
Feedstock
biosynthetic (enzymatic conversion of hydroquinone and glucose)
Related Ingredients
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Quick Reference
- Full INCI Name
- Alpha-Arbutin
- Common Name
- Alpha Arbutin
- CAS Number
- 84380-01-8
- Category
- actives