ph adjusters

Arginine

L-Arginine

ph adjusterskin protectantconditioninghumectant
CAS Number:74-79-3

INCI Name

Arginine

Functions

4 Roles

Sustainability

8/10

Category

ph adjusters

What It Does

Arginine is a semi-essential amino acid that serves as a highly effective pH adjuster in cosmetic formulations, capable of neutralizing acidic ingredients while simultaneously providing skin conditioning benefits. Unlike simple alkaline pH adjusters, arginine enhances skin hydration through its humectant properties and supports the skin's natural moisture barrier. Formulators favor arginine because it offers a gentler alternative to traditional bases like sodium hydroxide, while also contributing to improved skin feel and potential anti-aging benefits through its role in collagen synthesis.

Optimizes formula stability
Ensures skin compatibility
Maximizes ingredient efficacy
Prevents irritation

Technical Properties

pH Range

10.5-12.0

Optimal working range

Ionic Charge

cationic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Molecular Profile

Molecular Weight

174.20

g/mol

LogP

-4.20

Partition coefficient (lipophilicity)

H-Bond Donors

4

Hydrogen bond donor count

H-Bond Acceptors

4

Hydrogen bond acceptor count

Polar Surface Area

128.0

Angstroms squared

PubChem CID

6322

View on PubChem

Ingredient Compatibility

Known Interactions

DIHYDROXYACETONEIncompatiblemaillard_degradation

DHA undergoes Maillard browning with free amino acids on skin to produce melanoidins (the tan). Free amino acids IN THE FORMULA (aloe vera juice, hydrolyzed proteins, peptide complexes, amino acid blends) react with DHA pre-application, degrading the active and accelerating off-smell development over shelf life. Remove the amino-acid source, switch to glycerin/propanediol/sodium PCA for hydration, or use encapsulated DHA if the amino-acid ingredient is brand-critical.

Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

8/10

Biodegradability

readily biodegradable

Source

fermentation

Feedstock

plant-based sugars or synthetic production

Quick Reference

Full INCI Name
Arginine
Common Name
L-Arginine
CAS Number
74-79-3
Category
ph adjusters

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