activesAnhydrous Fine Powder, USP Grade (dissolve in heated water phase at 70°C; solubility limit ~2.2% at 25°C, fully soluble at processing temp, remains in solution upon cooling with glycol co-solvents)

Caffeine

Caffeine

Key active; vasoconstrictor appearance that visibly reduces puffiness and dark circles

INCI Name

Caffeine

Functions

1 Roles

Sustainability

7/10

Category

actives

What It Does

Caffeine is a naturally occurring methylxanthine alkaloid most commonly sourced from coffee beans and tea leaves, or recovered as a byproduct of industrial decaffeination. In cosmetic formulations, it is uniquely valued for its ability to inhibit phosphodiesterase, thereby promoting lipolysis in adipocytes and transiently constricting blood vessels — mechanisms that underpin its visible reduction of under-eye puffiness and dark circles. Formulators favor the anhydrous USP-grade powder for its high purity, reliable bioactivity, and the fact that it remains stably solubilized at use concentrations (typically 0.5–2%) when processed in a heated aqueous phase with glycol co-solvents.

Enhances formula performance
Contributes to product quality
Supports formulation goals
Improves user experience

Technical Properties

pH Range

5.0-7.0

Optimal working range

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Foaming Ability

none

Lather generation

Ingredient Compatibility

Known Interactions

EPHEDRINEIncompatibleSafety Concern

Caffeine + Ephedrine combination is banned by FDA due to cardiovascular risk (hypertension, tachycardia, stroke). Never combine in any consumer product.

Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

plant-derived

Feedstock

Primarily extracted from coffee beans (Coffea arabica/canephora), tea leaves (Camellia sinensis), or recovered as a byproduct of decaffeination processes; synthetic routes also exist but are less common in cosmetics

Available Variants

8 forms available

Anhydrous Fine Powder, USP Grade (dissolve in heated water phase at 70°C; solubility limit ~2.2% at 25°C, fully soluble at processing temp, remains in solution upon cooling with glycol co-solvents)

Anhydrous Powder

Fine Powder

Fine Powder, Anhydrous, USP Grade

Powder

Powder 99%

Standard

Anhydrous Fine Powder, USP Grade

Quick Reference

Full INCI Name
Caffeine
Common Name
Caffeine
Category
actives

Make something with this

Pitch an idea.
We'll help you build the brand.

Start your idea
Caffeine (Caffeine) - Key active; vasoconstrictor appearance that visibly reduces puffiness and dark circles | Genie Ingredient Database