skin conditioning

CHLOROSALICYLIC ACID

skin conditioning
CAS Number:321-14-2

INCI Name

CHLOROSALICYLIC ACID

Functions

1 Roles

Sustainability

N/A

Category

skin conditioning

What It Does

5-chlorosalicylic acid

Molecular Profile

Molecular Weight

172.56

g/mol

LogP

3.10

Partition coefficient (lipophilicity)

H-Bond Donors

2

Hydrogen bond donor count

H-Bond Acceptors

3

Hydrogen bond acceptor count

Polar Surface Area

57.5

Angstroms squared

PubChem CID

9447

View on PubChem

Ingredient Attributes

Ingredient Compatibility

Known Interactions

RETINOLUse CautionpH Conflict

Retinol and Salicylic Acid together increase irritation risk. Salicylic Acid's optimal pH (2.5-4) destabilizes Retinol. Best used in separate routines.

GLYCOLIC ACIDUse CautionIrritation Risk

Combining AHA (Glycolic) and BHA (Salicylic) at full concentrations significantly increases irritation risk and can compromise the skin barrier. If combining, reduce concentrations of both.

LACTIC ACIDUse CautionIrritation Risk

Combining AHA (Lactic) and BHA (Salicylic) increases exfoliation beyond what most skin can tolerate. Reduce concentrations if combining, or use in separate products.

TRETINOINUse CautionIrritation Risk

Tretinoin combined with Salicylic Acid causes excessive exfoliation and irritation. Both are potent actives that thin the stratum corneum. Do not combine at full strength.

Compatibility analysis powered by OpenMix — open-source formulation science

Make something with this

Pitch an idea.
We'll help you build the brand.

Start your idea