INCI Name
ACETYL TETRAPEPTIDE-...
Functions
2 Roles
Sustainability
6/10
Category
actives
What It Does
Acetyl Tetrapeptide-3 is a synthetic biomimetic peptide composed of four amino acids with an acetyl group at the N-terminus, specifically designed to target hair follicle anchoring and scalp health. It works by stimulating extracellular matrix proteins such as laminin-5 and collagen IV in the dermal papilla, helping to strengthen the attachment of hair follicles to the scalp and reduce hair loss. Formulators choose it primarily for anti-hair loss and scalp treatment products, often combining it with other actives like biotinoyl tripeptide-1, as it addresses follicle anchoring through a distinct and complementary mechanism of action.
Technical Properties
pH Range
5.0-7.0
Optimal working range
Ionic Charge
nonionic
Molecular charge type
Viscosity Effect
neutral
Impact on formula thickness
Foaming Ability
none
Lather generation
Molecular Profile
Molecular Weight
509.60
g/mol
LogP
-3.00
Partition coefficient (lipophilicity)
H-Bond Donors
8
Hydrogen bond donor count
H-Bond Acceptors
8
Hydrogen bond acceptor count
Polar Surface Area
240.0
Angstroms squared
Ingredient Compatibility
Works Well With
Avoid Combining
Sustainability Profile
Sustainability Score
Biodegradability
readily biodegradable
Source
synthetic
Feedstock
Synthetically produced tetrapeptide composed of acetylated amino acid sequence (Gly-His-Lys derivative), typically manufactured via solid-phase peptide synthesis
Related Ingredients
Similar conditionings to explore
Quick Reference
- Full INCI Name
- ACETYL TETRAPEPTIDE-3
- Common Name
- Acetyl Tetrapeptide-3
- Category
- actives