actives

Ceramide AP

Ceramide AP

skin protectantemollientconditioning
CAS Number:212070-45-6

INCI Name

Ceramide AP

Functions

3 Roles

Sustainability

7/10

Category

actives

What It Does

Ceramide AP (also known as Ceramide 6 II or Ceramide 6) is a synthetic lipid that mimics the alpha-hydroxy fatty acid ceramides naturally found in the skin's stratum corneum. It features a unique phytosphingosine base linked to an alpha-hydroxy fatty acid, making it particularly effective at restoring the skin's barrier function and reducing transepidermal water loss. Formulators choose Ceramide AP specifically for its ability to improve skin barrier integrity in combination with other ceramides (particularly Ceramide NP and Ceramide EOP) and cholesterol, creating a biomimetic lipid matrix that closely resembles natural skin composition.

Creates protective barrier
Shields from environmental stress
Reduces irritation risk
Supports skin recovery

Technical Properties

Ionic Charge

nonionic

Molecular charge type

Viscosity Effect

neutral

Impact on formula thickness

Molecular Profile

Molecular Weight

600.00

g/mol

LogP

12.60

Partition coefficient (lipophilicity)

H-Bond Donors

5

Hydrogen bond donor count

H-Bond Acceptors

5

Hydrogen bond acceptor count

Polar Surface Area

110.0

Angstroms squared

PubChem CID

44625889

View on PubChem

Ingredient Compatibility

Works Well With

nonionic emulsifiersemollientsother ceramidescholesterolfatty acidshumectantsantioxidants

Avoid Combining

strong acidsstrong basesstrong oxidizers
Compatibility analysis powered by OpenMix — open-source formulation science

Sustainability Profile

Sustainability Score

7/10

Biodegradability

readily biodegradable

Source

synthetic

Feedstock

plant-derived fatty acids and sphingoid bases

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